| Autor: |
McGovren, J. Patrick, Nelson, Kenneth G., Lassus, Mercedes, Cradock, James C., Plowman, Jacqueline, Christopher, John P. |
| Zdroj: |
Investigational New Drugs; December 1984, Vol. 2 Issue: 4 p359-367, 9p |
| Abstrakt: |
Menogaril [menogarol, 7(R)-O-methymogarol, 7-OMEN] is a new anthracycline agent which was chosen for clinical trials based on:a)broad spectrum activity against a panel of murine tumorsb)lower cardiotoxicity than doxorubicin in the chronic rabbit modelc)differences in biochemical effects from other anthracyclines suggesting a possible difference in mechanism of actiond)murine antitumor activity by oral as well as parenteral routes. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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