| Autor: |
Pashazadeh, Mehdi, Butler, Keith D., Kidner, Peter H. |
| Zdroj: |
Lasers in Medical Science; March 1988, Vol. 3 Issue: 1-4 p143-149, 7p |
| Abstrakt: |
The platelet response and fibrin deposition following the delivery of an argon-ion laser beam to the rabbit ear artery has been evaluated kinetically using a minimally invasive technique utilizing51Cr-labelled platelets and125I-labelled human fibrinogen. After laser irradiation there was an immediate increase in platelet-associated radioactivity which was followed by a series of transient increases and decreases suggesting that micro-embolization was occurring. When fibrin deposition was studied, there was a lag time of six minutes before rapid deposition of fibrin. However, once the increase in radioactivity was established the series of transient increases and decreases previously observed with51Cr-labelled platelets was not observed using125I-labelled human fibrinogen. Histological examination of the arteries confirmed platelet accumulation and fibrin deposition. Our findings confirm that platelet accumulation with probable microembolization and fibrin deposition occurs following laser angioplasty. |
| Databáze: |
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