| Autor: |
Greenfield, P. F., Guillaume, J. -M., Randerson, D. H., Smith, C. G. |
| Zdroj: |
Bioprocess and Biosystems Engineering; June 1991, Vol. 6 Issue: 5 p213-219, 7p |
| Abstrakt: |
A perfusion system for production of monoclonal antibodies was developed using an externally-mounted, hollow-fibre cartridge. The experimental apparatus was operated for 420 h and demonstrated increased steady-state viable cell concentration with increase in perfusion rate. Antibody titres were up to three times those measured for batch cultures and specific antibody productivity was doubled. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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