Intracellular Delivery of Nanogel-Quantum Dot Hybrid Nanoparticles into Human Periodontal Ligament Cells

Autor: Fukui, Tomoe, Kobayashi, Hiroaki, Hasegawa, Urara, Nagasawa, Toshiyuki, Akiyoshi, Kazunari, Ishikawa, Isao
Zdroj: Drug Metabolism Letters; April 2007, Vol. 1 Issue: 2 p131-135, 5p
Abstrakt: Nanogels of cholesterol-bearing pullulan modified with amino-groups (CHPNH2) were utilized as a career to introduce quantum dots (QDs) into periodontal ligament (PDL) cells. Nanogel-QD effectively labeled PDL cells over 3 weeks. These results indicate that CHPNH2nanogels have a potential as a research tool in the studies of intracellular delivery system.
Databáze: Supplemental Index