| Autor: |
Lan, S. J., Weliky, I., Schreiber, E. C. |
| Zdroj: |
Xenobiotica; 1973, Vol. 3 Issue: 2 p97-102, 6p |
| Abstrakt: |
1. Reductive cleavage of the oxadiazole ring of trans-5-amino-3-[2-(5-nitro-2-furyl)vinyl]-1,2,4-[5-14C]oxadiazole (SQ 18,506-14C) has been demonstrated both enzymically and chemically.2. Oral administration of SQ 18,506-14C to humans and rat resulted in the formation of respiratory 14CO2 and the excretion of 14C-urea in the urine.3. Formation of 14CO2 was demonstrated in vitro by incubation of SQ 18,506-14C with homogenate of human or mouse liver or with milk xanthine oxidase.4. 14C-urea was isolated after reduction of SQ 18,506-14C by ferrous hydroxide. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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