| Autor: |
Kufahl, Jan, Pedersen, Ivan, Eriksen, Poul Sindberg, Helkjaer, Poul Erik, Larsen, Lise Grupe, Jensen, Karen Linnert, de Nully, Pia, Philipsen, Torben, Wåhlin, Anne |
| Zdroj: |
Acta Obstetricia et Gynecologica Scandinavica; 1997, Vol. 76 Issue: 8 p790-796, 7p |
| Abstrakt: |
Background. The purpose of this study was to evaluate the diagnostic value of transvaginal ultrasound measurement of endometrial thickness, cytology obtained by Gynoscannr`, and histology of the endometrium sampled by Uterine Explora Curetter`compared with histology of the uterine specimen as the gold standard.Methods. Consecutive patients admitted for hysterectomy had transvaginal ultrasound, sampling by Gynoscannr`, and Uterine Explora Curetter`done just before surgery, after informed consent.Results. A total of 181 women entered the study. Sixteen had endometrial cancer, seven had atypical hyperplasia and nine had complex hyperplasia. A total of 168 patients had a transvaginal ultrasound done. At a cutoff limit of 4mm (endometrial thickness of 4mm or less indicating normal endometrium), the sensitivity was 90.3%, the specificity 24.8%, the positive predictive value 21.4% and the negative predictive value 91.9%. One endometrial cancer, one atypical and one complex hyperplasia were missed. The Gynoscannr`method showed a sensitivity of 62.5%, a specificity of 94.0%, a positive predictive value of 69.0% and a negative predictive value of 92.1%. Two cancers, three atypical and six complex hyperplasia were missed. The Uterine Explora Curetter`showed a sensitivity of 90.6%, a specificity of 100.0%, a positive predictive value of 100.0% and a negative predictive value of 98.0%. One endometrial cancer and two complex hyperplasia were missed.Conclusion. Transvaginal ultrasound is a reliable method in excluding endometrial pathology. The Uterine Explora Curetter`was superior to Gynoscannr`in diagnosing neoplasia of the endometrium. It was found to have the same diagnostic accuracy as conventional dilatation and curettage. |
| Databáze: |
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