Synthesis and Characterization of Phosphonic Acid-Substituted Amino Acids as Excitatory Amino Acid Receptor Antagonists

Autor: Ornstein, Paul, Arnold, M. Brian, Allen, Nancy, Schoepp, Darryle
Zdroj: Phosphorus, Sulfur, and Silicon and the Related Elements; February 1996, Vol. 109 Issue: 1 p309-312, 4p
Abstrakt: Decahydroisoquinoline-3-carboxylic acids, substituted at C-6 with an acidic moiety such as a phosphonic, sulfonic or carboxylic acid or tetrazole, were prepared as antagonists of excitatory amino acid (EAA) receptors.
Databáze: Supplemental Index