| Autor: |
Wurz, R. E. M., Kepner, R. E., Webb, A. D. |
| Zdroj: |
Preparative Biochemistry & Biotechnology; January 1989, Vol. 19 Issue: 3 p209-215, 7p |
| Abstrakt: |
A stereospecific synthesis of 4-14C-l-glutamic acid was completed in five steps from sodium 2-14C-acetate. The morpholine derived enamine of ethyl pyruvate was reacted with ethyl 2-14C-bromoacetate to give after hydrolysis diethyl 4-14C-2-oxoglutarate. The 2-oxoglutarate was reacted with hydroxylamine hydrochloride to give diethyl 4-14C-2-hydroxyiminoglutarate which was then reduced with a LiAlH4, (-)-N-methylephedrine and 3,5-dimethylphenol mixture to give 4-14C-1-glutamic acid. The 4-14C-1-glutamic acid was used in investigations into the biosynthesis of gamma-lactones in sherries. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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