| Autor: |
Bokkenheuser, V. D., Motyl, M., Van Horn, K., Johnson, J. L., Winter, J. |
| Zdroj: |
Microbial Ecology in Health and Disease; October 1989, Vol. 2 Issue: 4 p241-246, 6p |
| Abstrakt: |
In recent years, strains of different Clostridia species capable of metabolising steroids have been isolated from human faecal flora and from sewage. The organisms (enzymes) are C.cadaveris (20β-reductase and C17-C20 desmolase); C. sporogenes (C21-hydroxy-acetylase); C.paraputrificum (3α-hydroxy-5β-reductase, chemically known as hydroxy steroid dehydrogenase, HSDH) and C.innocuum (3β,5β-HSDH). Examination of type and stock culture strains from different sources demonstrated that synthesis of steroid metabolising enzymes was characteristic for the species. Of sixteen type/neotype strains not previously reported to synthesise steroid active enzymes, fourteen produced a C21 hydroxy acetylase, and two, C.glycolicum and C.carnis, a 3α, 5β-HSDH. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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