| Autor: |
R. Pettit, George, J. R. V. Mukku, Venugopal, Cragg, Gordon, L. Herald, Delbert, C. Knight, John, L. Herald, Cherry, Chapuis, Jean-Charles |
| Zdroj: |
Journal of Natural Products; January 2008, Vol. 71 Issue: 1 p130-133, 4p |
| Abstrakt: |
An investigation of the Phillippine Ampelocissussp. roots for cancer cell growth inhibitory components led to the isolation of a new acetogenin characterized as 22-epicalamistrin ( 1) employing primarily 2D NMR and high-resolution mass spectral analysis. Two other antineoplastic constituents proved to be the known acetogenin uvaribonin ( 2) and chalcone 3. Constituents 1– 3were all found to show significant cancer cell growth inhibitory activity against a panel of human cancer cell lines. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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