Effect of Enterosorption on Animal Lifespan

Autor: Frolkis, V. V., Nikolaev, V. G., Paramonova, G. I., Shchorbitskaya, E. V., Bogatskaya, L. N., Stupina, A. S., Kovtun, A. I., Sabko, V. E., Shaposhnikov, V. M., Muradian, Kh., Adamenko, N. P., Novikova, S. M., Koltovor, V. K., Gorban, S. N.
Zdroj: Artificial Cells, Blood Substitutes, and Biotechnology; 1989, Vol. 17 Issue: 3 p341-351, 11p
Abstrakt: Experiments were performed on Wistar male rats, starting from the 28th month of age. The effect of dietary sorbent (non coated nitrogen-containing carbon administered as 10 day courses at 1 month intervals in dosage of 10 ml/kg) on lifespan and a number of biological indices were studied. Enterosorption resulted in the increase of mean and maximal lifespan by 43 and 34% respectively. Analysis of the effect of enterosorption on activity of microsomal enzymes, intensity of total RNA and protein biosynthesis, lipid metabolism, formation of free radicals etc. showed that it produced a positive influence on the functional state of the studied systems and increased the organism's adaptive capacities. Enterosorption was found to delay the rate of onset of age-related structural changes in the organs and tissues.
Databáze: Supplemental Index