In vitro investigations with selective adsorbents for IgE and IgM

Autor: Behm, E., Kuroda, T., Yamawaki, N., Tsuda, N., Loth, F., Schwachula, G., Sabrowski, E., Falkenhagen, D., Klinkmann, H.
Zdroj: Artificial Cells, Blood Substitutes, and Biotechnology; 1987, Vol. 15 Issue: 1 p101-111, 11p
Abstrakt: In vitro studies were carried out with IM-T. This adsorbent consists of polyvinyl alcohol joined with tryptophan side chains and was delivered by ASAHI Medical Co., Ltd., Tokyo/Japan.It was found that IM-T binds immunoglobulins G and M and also immune complexes only moderately but IgE was adsorbed in remarkable amounts. A clear dosedependent manner of the IgE adsorption could be stated. Kinetic studies revealed that the binding was only slow and gradual.
Databáze: Supplemental Index