The three-dimensional structure of the antigen-binding fragment of a monoclonal antibody to human interleukin-2 in two crystal forms at 2.2 and 2.9 Å resolution

Autor: Fokin, A. V., Afonin, P. V., Mikhailova, I. Yu., Tsygannik, I. N., Mareeva, T. Yu., Nesmeyanov, V. A., Pangborn, W., Lee, N., Duax, W., Ciszak, E., Pletnev, V. Z.
Zdroj: Russian Journal of Bioorganic Chemistry; September 2000, Vol. 26 Issue: 9 p512-519, 8p
Abstrakt: The three-dimensional structure of the antigen-binding fragment of a monoclonal antibody to human interleukin-2 was determined in two crystal forms by the X-ray method of molecular replacement at 2.2 and 2.9 Å resolutions. The spatial structure of the protein and the stereochemistry of its antigen-binding site were analyzed.
Databáze: Supplemental Index
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