| Autor: |
DELACRÉTAZ, F., STALDER, M., MEUGÉ‐MORAW, C., SCHMIDT, P.M., JORIS, F., KURT, A.‐M., DE WERRA, P. |
| Zdroj: |
Histopathology; June 1997, Vol. 30 Issue: 6 p582-584, 3p |
| Abstrakt: |
Cases of mediastinal germ cell tumours associated with haematological disorders (two cases of systemic mastocytosis included) have been reported previously. This combination is more frequent than would be expected by chance alone. We report the case of a 30‐year‐old woman, who presented with a systemic mastocytosis following a malignant ovarian germ cell tumour which was treated by chemo‐ and radiotherapy. The patient predominantly complained of skeletal pains, which led to an erroneous radiological diagnosis of fibrous dysplasia for years. An aggressive variant of systemic mastocytosis was diagnosed on bone marrow examination. Systemic mastocytosis was confirmed by splenectomy, liver biopsy and finally autopsy. The present case is unique because of the ovarian location of the germ cell tumour. We suggest our observation could be related to the broad group of haematological malignancies associated with germ cell tumours. |
| Databáze: |
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