Palladium-Catalyzed Coupling Reaction of Iodouracil Having Acetamidine Moiety with Olefins

Autor: Roh, YoungHae, Bae, JongWoo, Nam, GilSoo, Kim, JoongHyup, Kim, SungHoon, Yoon, CheolMin
Zdroj: Synthetic Communications; January 2000, Vol. 30 Issue: 1 p81-86, 6p
Abstrakt: AbstractThe reaction of 6-[1-Aza-2-(dimethylamino)prop-l-enyl]-5-iodo-1,3-dimethyluracil (3) with various olefins in the presence of a catalytic amount of Pd(OAc)2and 1.5 equiv. of K2CO3in DMF at 120 °C gave the pyrido[2,3-d]pyrimidine derivatives (5a-b and 7a-d) in moderate to high yield.
Databáze: Supplemental Index