| Autor: |
Korshunov, V. A., Murashev, A. N., Ivashev, M. N., Dugin, S. F., Medvedev, O. S. |
| Zdroj: |
Bulletin of Experimental Biology and Medicine; August 2000, Vol. 130 Issue: 8 p777-779, 3p |
| Abstrakt: |
Single intravenous injection of antidepressant tetrindol (1 and 10 mg/kg), a reversible monoamine oxidase A inhibitor, dose-dependently decreased heart rate and mean arterial pressure (in a concentration of 10 mg/kg) in alert NMRI mice and Sprague-Dawley rats. Nitric oxide synthase blockade with L-NAME attenuated tetrindol-induced bradycardia in rats and completely abolished this effect in mice. |
| Databáze: |
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