Antiseea to Carcinoembryonic Antigen: Removal of Persistant Impurities (1)

Autor: Hetrick, Daniel, Miller, Kent
Zdroj: Immunological Investigations; 1974, Vol. 3 Issue: 5 p489-495, 7p
Abstrakt: Antisera to carcinoembryonic antigen preparations frequently contained antibodies to a distinct normal serum protein(s). The latter antibodies persisted following absorptions with cross-linked human plasma proteins, normal colon, and Group 0 red cells. A simple method for removal of the contaminating antibodies involved absorptions with the perchloric acid-soluble fraction of normal serum. Excesses of the absorbant and its soluble immune complexes were then removed on anion exchange columns.
Databáze: Supplemental Index