Atrazine in Plasma and Tissue Following Atrazine-Aminotriazole-Ethylene Glycol-Formaldehyde Poisoning

Autor: Pommery, Jean, Mathieu, Monique, Mathieu, Daniel, Lhermitte, Michel
Zdroj: Clinical Toxicology; 1993, Vol. 31 Issue: 2 p323-331, 9p
Abstrakt: A high performance liquid chromatography method has been used to study the plasma kinetics of atrazine in a human fatality after ingestion of a herbicide mix containing atrazine, aminotriazole, ethylene glycol and formaldehyde. A hemodialysis was performed in an effort to eliminate these toxic substances. The mean atrazine clearance over 4 h was 250 mL/min and the dialysance of atrazine was calculated as 76%. On autopsy, the kidney showed the highest concentration of atrazine (97.62 μg/g-1 wet tissue) with lesser concentrations in the lung, small intestine and liver, and the lowest concentration in the heart.
Databáze: Supplemental Index