| Abstrakt: |
Two new steroidal sulfates, eurysterols A (1) and B (2), were isolated from an undescribed marine sponge of the genus Euryspongiacollected in Palau. The structures of the new compounds were assigned by NMR spectroscopic data interpretation. Compounds 1and 2showed cytotoxicity against human colon carcinoma (HCT-116) cells with IC50values of 2.9 and 14.3 g/mL, respectively, and exhibited antifungal activity against amphotericin B-resistant and wild-type strains of Candida albicanswith MIC values, in turn, of 15.6 and 62.5 g/mL. |
