Bioactive Compounds from Bauhinia purpureaPossessing Antimalarial, Antimycobacterial, Antifungal, Anti-inflammatory, and Cytotoxic Activities

Autor: Boonphong, Surat, Puangsombat, Pakawan, Baramee, Apiwat, Mahidol, Chulabhorn, Ruchirawat, Somsak, Kittakoop, Prasat
Zdroj: Journal of Natural Products; May 2007, Vol. 70 Issue: 5 p795-801, 7p
Abstrakt: Eleven new secondary metabolites (1−11), together with two known flavanones (12and 13) and five known bibenzyls (14−18), were isolated from the root extract of Bauhinia purpurea. New compounds include eight dihydrodibenzoxepins (1−8), a dihydrobenzofuran (9), a novel spirochromane-2,1‘-hexenedione (10), and a new bibenzyl (11). Antimycobacterial, antimalarial, antifungal, cytotoxic, and anti-inflammatory activities of the isolated compounds are reported, and biosynthetic pathways of these compounds are also discussed.
Databáze: Supplemental Index