The Formation of Photoreactivable Damage by Direct Excitation of DNA in X-irradiated E. Coli Cells

Autor: Duba, V. V., Pitkevich, V. A., Selyova, N. G., Petrova, I. V., Myasnik, M. N.
Zdroj: International Journal of Radiation Biology; 1985, Vol. 47 Issue: 1 p49-56, 8p
Abstrakt: The role of the direct excitation process in the formation of photoreactivable damage (pyrimidine dimers) in E. coli WP2 hcr-exr- cells has been studied. The pyrimidine dimers were detected by photoreactivation following anoxic irradiation by X-rays (220 kVp). The dose modifying factor (DMF) is 1·28 ± 0·09. A biophysical model is used for a theoretical examination of the importance of the direct excitation process in the formation of photoreactivable damage and the experimental data are consistent with this model.
Databáze: Supplemental Index