| Autor: |
Patrick, G., Carr, T. E. F., Humphreys, E. R. |
| Zdroj: |
International Journal of Radiation Biology; 1967, Vol. 12 Issue: 5 p427-434, 8p |
| Abstrakt: |
Slices of rat duodenum were incubated in a medium containing the sodium salt of an alginate and tracer amounts of 85Sr and 45Ca. Alginate inhibited the uptake of 85Sr by the slices more than it did that of 45Ca. The uptake of 85Sr decreased as the guluronic acid content of the alginate increased, but the uptake of 45Ca was not affected. The degree of polymerization of the alginate had no influence on the uptake of either isotope.When fed to rats at 10 per cent of the diet, an alginate containing 97 per cent of guluronic acid decreased the absorption of 85Sr to 0·16 of the control value without significantly changing calcium absorption.The rat intestinal wall was shown to be impermeable to this alginate by the everted sac technique. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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