Ductal lavage: a way of carefully tracing the breast-secreting duct

Autor: Russo, Antonio, Gregorio, Valter, Sisto, Pasqua Sandra, Calòò, Valentina, Agnese, Valentina, Augello, Claudia, Cascio, Sandra, Badalamenti, Giuseppe, Fricano, Salvatore, Napoli, Liborio, Giordano, Antonio, Santini, Daniele, Gebbia, Nicola, Bazan, Viviana
Zdroj: Therapy; May 2006, Vol. 3 Issue: 3 p389-393, 5p
Abstrakt: Background:Breast cancer is the most commonly diagnosed neoplasia in women after nonmelanoma skin tumors. Unfortunately, present-day diagnostic methods are unable to identify the presence of a cancer until it has been developing for several  years. Currently, ductal lavage seems to represent a new method of reaching an early diagnosis of breast cancer. Materials & methods: This study analyzed 30 patients with ages ranging from 40  to 55  years; and in 26 of these patients, we were able to obtain a sufficient quantity of material for cytological and biomolecular analysis. Results & conclusion: We propose an easy, reproducible method that makes it possible to obtain a detailed map of the nipple, in order to re-identify the duct orifice and take a series of repeated samples from it over a period of time. This procedure is a promising screening and translational research tool since it provides the quantity and quality of ductal fluid required for subsequent cytological and biomolecular analyses.
Databáze: Supplemental Index