| Autor: |
Williams, D. R., Fromhold, M. G., Earley, J. D. |
| Zdroj: |
Organic Letters; August 2001, Vol. 3 Issue: 17 p2721-2724, 4p |
| Abstrakt: |
A stereocontrolled total synthesis of the polycyclic Stemona alkaloid, (−)-stemospironine (1) has been achieved. Key transformations include the use of a Staudinger reaction leading to the aza-Wittig ring closure of the perhydroazepine system. Formation of the vicinal pyrrolidine butyrolactone is described via the stereoselective intramolecular capture of an intermediate aziridinium salt. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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