An Approach to the Skeleton of the Securinega Alkaloids. The Total Synthesis of (±)-Securinine

Autor: Liras, S., Davoren, J. E., Bordner, J.
Zdroj: Organic Letters; March 2001, Vol. 3 Issue: 5 p703-706, 4p
Abstrakt: The concise total synthesis of securinine in nine steps from readily available starting materials is described. Key steps of the synthesis include an addition of a silyloxyfuran to an in situ generated iminium ion and a novel ring closing metathesis reaction.
Databáze: Supplemental Index