Palladium and Raney Nickel Catalyzed Methanolic Cleavage of Stable Borane−Amine Complexes

Autor: Couturier, M., Tucker, J. L., Andresen, B. M., Dube, P., Negri, J. T.
Zdroj: Organic Letters; February 2001, Vol. 3 Issue: 3 p465-467, 3p
Abstrakt: Palladium and Raney nickel were found to catalyze the methanolysis of borane−amine adducts. Hence, strongly complexed amines can now be liberated by simple treatment with Pd/C or Raney Ni in methanol. The method is applicable to primary, secondary, tertiary, and aromatic amines, and the mildness of the reaction conditions allows preservation of otherwise labile functional groups.
Databáze: Supplemental Index