| Autor: |
McCloskey, J.A., Whitehill, A.B., Rozenski, J., Qiu, F., Crain, P.F. |
| Zdroj: |
Nucleosides and Nucleotides; June 1999, Vol. 18 Issue: 6-7 p1549-1553, 5p |
| Abstrakt: |
AbstractRecent advances in combined HPLC/electrospray ionization-mass spectrometry provide effective new capabilities for the rapid characterization of oligonucleotides. Accurate mass measurements with errors <0.3 Da, and determination of base and sugar modification and of nearest neighbor identities, can be routinely carried out on 10-100 component mixtures of RNA or DNA. These procedures are widely applicable in structural and analytical studies involving mixtures of oligonucleotides. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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