6-N-1 Trobenzotriazol-1-Yloxytris(Dimethylamino)Phosphonium Hexafluorophosphate (NBOP): A New Coupling Reagent in Oligonucleotide Synthesis

Autor: Hashmi, S. A. Nadeem, Adiraj, M., Kumar, Anil, Katti, S. B.
Zdroj: Nucleosides and Nucleotides; June 1994, Vol. 13 Issue: 5 p1059-1067, 9p
Abstrakt: 6-Nitrobenzotriazol-1-yloxytris(dimethylamino) phosphonium hexafluorophosphate (NBOP, 2) has been demonstrated as an efficient coupling reagent in oligonucleotide synthesis. The reagent is stable and gives high coupling yields without any side products.
Databáze: Supplemental Index