Synthesis and Separation of Dinucleoside Phenylphosphonate Diastereomers
Autor: | Hashmi, S. A. Nadeem, Kumar, Anil, Kacti, S. B. |
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Zdroj: | Nucleosides and Nucleotides; June 1994, Vol. 13 Issue: 5 p1039-1047, 9p |
Abstrakt: | Dinucleoside phenylphosphonates have been synthesized in excellent yields using 6-Nitrobenzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate (NBOP) as a coupling reagent. A general method for the resolution of two diastereomers of phenylphosphonate dimers has been developed. |
Databáze: | Supplemental Index |
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