Synthesis and Separation of Dinucleoside Phenylphosphonate Diastereomers

Autor: Hashmi, S. A. Nadeem, Kumar, Anil, Kacti, S. B.
Zdroj: Nucleosides and Nucleotides; June 1994, Vol. 13 Issue: 5 p1039-1047, 9p
Abstrakt: Dinucleoside phenylphosphonates have been synthesized in excellent yields using 6-Nitrobenzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate (NBOP) as a coupling reagent. A general method for the resolution of two diastereomers of phenylphosphonate dimers has been developed.
Databáze: Supplemental Index