| Autor: |
Crimmins, M. T., Emmitte, K. A., Katz, J. D. |
| Zdroj: |
Organic Letters; July 2000, Vol. 2 Issue: 14 p2165-2167, 3p |
| Abstrakt: |
The diastereoselective alkylation of glycolate oxazolidinones has been demonstrated as a method for the enantioselective preparation of α-alkoxy carboxylic acid derivatives and selectively protected 1,2-diols. Various protecting groups on the glycolate hydroxyl and multiple substitution patterns on allylic iodides are tolerated in the alkylation. Yields for the alkylations are typically 70−85% with diastereoselectivities of >98:2. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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