| Autor: |
Nilsson, B. L., Kiessling, L. L., Raines, R. T. |
| Zdroj: |
Organic Letters; June 2000, Vol. 2 Issue: 13 p1939-1941, 3p |
| Abstrakt: |
The technique of native chemical ligation enables the total chemical synthesis of proteins. This method is limited, however, by an absolute requirement for a cysteine residue at the ligation juncture. Here, this restriction is overcome with a new chemical ligation method in which a phosphinobenzenethiol is used to link a thioester and azide. The product is an amide with no residual atoms. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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