Synthesis of the Apoptosis Inducing Agent Apoptolidin. Assembly of the C(16)−C(28) Fragment

Autor:	Sulikowski, G. A., Lee, W.-M., Jin, B., Wu, B.
Zdroj:	Organic Letters; May 2000, Vol. 2 Issue: 10 p1439-1442, 4p
Abstrakt:	A stereoselective synthesis of the C(16)−C(28) fragment of the apoptosis inducing agent apoptolidin is described. Key steps include two propionate aldol reactions and a stereoselective Mukaiyama aldol addition of enolsilane 19 to β-methoxy aldehyde 4.
Databáze:	Supplemental Index
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