| Autor: |
Baldwin, S. W., Debenham, J. S. |
| Zdroj: |
Organic Letters; January 2000, Vol. 2 Issue: 2 p99-102, 4p |
| Abstrakt: |
The total syntheses of the amaryllidaceae alkaloids haemanthidine, pretazettine, and tazettine as optically pure enantiomers are reported. Using d-mannose as the starting material, the critical relative stereochemical relationships are established with an intramolecular nitrone−alkene cycloaddition reaction. The synthetic route leads successively to (−)-haemanthidine and then to (+)-pretazettine and (+)-tazettine, taking advantage of the well-established complex relationships among these three alkaloids. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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