| Autor: |
Cao, B., Xiao, D., Joullie, M. M. |
| Zdroj: |
Organic Letters; December 1999, Vol. 1 Issue: 11 p1799-1801, 3p |
| Abstrakt: |
Cyclopropylamines and substituted cyclopropylamines are important building blocks or substituents in a variety of biologically active compounds. Here, we report the facile syntheses of cyclopropylamines by Ti(II)-mediated intramolecular coupling of a terminal olefinic moiety and the N,N-dimethylcarboxamide moiety of amino acid derivatives. The products have novel and strained bicyclic structures. The yields were good (78−83%) for all three substrates with diastereomeric ratios of about 3:1. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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