| Autor: |
Chung, J. Y. L., Grabowski, E. J. J., Reider, P. J. |
| Zdroj: |
Organic Letters; December 1999, Vol. 1 Issue: 11 p1783-1785, 3p |
| Abstrakt: |
Sequential reactions of nitromethane via conjugate addition−elimination to β-trifloxy acrylates followed by Pd-catalyzed substitution of the resulting allyl nitro compounds with nucleophiles afforded homologation products at the β-position. 2-Naphthosultammethyl carbapenem, an anti-MRS carbapenem intermediate, was prepared in one pot from the corresponding 2-trifloxy compound. The scope and limitation of the one-pot method were investigated using several cyclic unsaturated esters and nucleophiles. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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