| Autor: |
Gracia, I. Storch de, Bobo, S., Martin-Ortega, M. D., Chiara, J. L. |
| Zdroj: |
Organic Letters; December 1999, Vol. 1 Issue: 11 p1705-1708, 4p |
| Abstrakt: |
A concise synthesis of trehazolin, its aglycon, trehalamine, and a known analogue has been developed starting from d-mannose. This new approach features a very stereoselective and high-yielding ketone−oxime ether reductive carbocyclization promoted by samarium diiodide as a key step for the preparation of the aminocyclitol component and a mild and very efficient intramolecular triflate displacement reaction for the construction of the oxazoline ring. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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