| Autor: |
Shen, X., Krasnoff, S. B., Lu, S., Dunbar, C. D., O'Neal, J., Turgeon, B. G., Yoder, O. C., Gibson, D. M., Hamann, M. T. |
| Zdroj: |
Journal of Natural Products; June 25, 1999, Vol. 62 Issue: 6 p895-897, 3p |
| Abstrakt: |
The new sesterterpenoid 6-epi-3-anhydroophiobolin B (1) and six known ophiobolins were isolated from the extracts of the fungus Cochliobolus heterostrophus race O. The structure of 6-epi-3-anhydroophiobolin B was deduced from analysis of spectral data and the structural characterization of dehydration and dimerization products. Ophiobolin A (2) showed potent activity in cytotoxicity assays and marginal activity in antimalarial assays. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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