| Autor: |
Chen, J. L., Blanc, P., Stoddart, C. A., Bogan, M., Rozhon, E. J., Parkinson, N., Ye, Z., Cooper, R., Balick, M., Nanakorn, W., Kernan, M. R. |
| Zdroj: |
Journal of Natural Products; October 1998, Vol. 61 Issue: 10 p1295-1297, 3p |
| Abstrakt: |
Two new iridoid glycosides (1 and 2), together with the known compounds barlerin (3) and verbascoside (4), were isolated from Barleria prionitis. The new iridoid glycosides were determined to be 6-O-trans-p-coumaroyl-8-O-acetylshanzhiside methyl ester (1) and its cis isomer (2) by using spectroscopic, especially 2D NMR, data. A 3:1 mixture of 1 and 2 was shown to have potent in vitro activity against respiratory syncytial virus (EC50 2.46 μg/mL, IC50 42.2 μg/mL). |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
