| Autor: |
Gentry, E. J., Jampani, H. B., Keshavarz-Shokri, A., Morton, M. D., Velde, D. Vander, Telikepalli, H., Mitscher, L. A., Shawar, R., Humble, D., Baker, W. |
| Zdroj: |
Journal of Natural Products; October 1998, Vol. 61 Issue: 10 p1187-1193, 7p |
| Abstrakt: |
Berberine (4) is responsible for the activity of an extract of a commercial root sample of Hydrastis canadensis against multiply drug resistant Mycobacterium tuberculosis. Two new quinic acid feruloyl esters, compounds 2 and 3, have been isolated from the same source along with canadine (1c), 8-oxotetrahydrothalifendine (1), and β-hydrastine (5). These were found to be inactive. The structures of the new compounds were elucidated from spectral (1H, 13C, HMQC, HMBC, and H−H COSY) and chemical evidences. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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