Lycaconitine Revisited:  Partial Synthesis and Neuronal Nicotinic Acetylcholine Receptor Affinities

Autor: Jacyno, J. M., Harwood, J. S., Lin, N.-H., Campbell, J. E., Sullivan, J. P., Holladay, M. W.
Zdroj: Journal of Natural Products; July 22, 1996, Vol. 59 Issue: 7 p707-709, 3p
Abstrakt: The norditerpenoid alkaloid lycaconitine (2) was synthesized from lycoctonine (3) and its affinity determined for two neuronal nicotinic acetylcholine receptor subtypes. The structure of 2 was confirmed by a combination of spectroscopic methods.
Databáze: Supplemental Index