An Improved Method for the Separation of Paclitaxel and Cephalomannine

Autor: Rimoldi, J. M., Molinero, A. A., Chordia, M. D., Gharpure, M. M., Kingston, D. G. I.
Zdroj: Journal of Natural Products; February 22, 1996, Vol. 59 Issue: 2 p167-168, 2p
Abstrakt: Treatment of a mixture of paclitaxel and cephalomannine with bromine under mild conditions yields a readily separable mixture of paclitaxel and 2‘‘,3‘‘-dibromocephalomannine. Cephalomannine can be regenerated by treating 2‘‘,3‘‘-dibromocephalomannine with zinc in acetic acid.
Databáze: Supplemental Index