Autor: |
Pflum, D. A., Wilkinson, H. S., Tanoury, G. J., Kessler, D. W., Kraus, H. B., Senanayake, C. H., Wald, S. A. |
Zdroj: |
Organic Process Research & Development; March 2001, Vol. 5 Issue: 2 p110-115, 6p |
Abstrakt: |
Enantiomerically pure cetirizine can be prepared by preparative HPLC separation of cetirizine amide. The amide has an α value of 2.76 (USP resolution of 8.54) using a Chiralpak AD column, and 0.5 wt % of the amide (based on packing material) can be injected per run. |
Databáze: |
Supplemental Index |
Externí odkaz: |
|