Scale-Up of an Intermolecular Barbier Reaction

Autor: Ennis, D. S., Lathbury, D. C., Wanders, A., Watts, D.
Zdroj: Organic Process Research & Development; September 1998, Vol. 2 Issue: 5 p287-289, 3p
Abstrakt: Addition of n-BuLi to a mixture of ketone (2) and 1,4-diiodobenzene provides access to alcohol (1) in high yield. This procedure has successfully been used on molar scale.
Databáze: Supplemental Index