| Autor: |
Cao, Shugeng, Norris, Andrew, S. Miller, James, Ratovoson, Fidy, Razafitsalama, Jeremi, Andriantsiferana, Rabodo, E. Rasamison, Vincent, TenDyke, Karen, Suh, Ted, G. I. Kingston, David |
| Zdroj: |
Journal of Natural Products; March 2007, Vol. 70 Issue: 3 p361-366, 6p |
| Abstrakt: |
Bioassay-guided fractionation of an EtOH extract obtained from the roots of the Madagascan plant Albizia gummiferaled to the isolation of three new cytotoxic oleanane-type triterpenoid saponins, gummiferaosides A−C (1−3). The structures of these new compounds were elucidated using 1D and 2D NMR experiments and mass spectrometry. Compounds 1−3showed cytotoxicity against the A2780 human ovarian cancer cell line with IC50values of 0.8, 1.5, and 0.6 g/mL, respectively. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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