Autor: |
Forquin, Marie-Pierre, Tazi, Asmae, Rosa-Fraile, Manuel, Poyart, Claire, Trieu-Cuot, Patrick, Dramsi, Shaynoor |
Zdroj: |
Infection and Immunity; April 2007, Vol. 75 Issue: 4 p2063-2066, 4p |
Abstrakt: |
Group B streptococcus (GBS) expresses a hemolysin/cytolysin that plays an important role in pathogenesis. Using the Himar1 transposon mutagenesis system, a hypohemolytic mutant carrying an interrupted cylJ gene was characterized. cylJ, encoding a putative glycosyltransferase, and cylK, whose product is unknown, are both required for the full hemolytic/cytolytic activity, pigment formation, and virulence of GBS. |
Databáze: |
Supplemental Index |
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