Synthesis and base recognition ability of oligoribonucleotides incorporating 2'-O-methyl-3-deazaguanosine

Autor: Seio, Kohji, Sasami, Takeshi, Sekine, Mitsuo
Zdroj: Nucleic Acids Symposium Series; November 2004, Vol. 48 Issue: 1 p65-65, 1p
Abstrakt: 2′-<it>O</it>-Methyl-Oligoribonucleotides incorporating a 3-deazaguanine (3DG) were synthesized. Melting temperature (Tm value) analysis indicates the stability and base discriminating ability of the 2′-<it>O</it>-methl-RNA/RNA duplex.
Databáze: Supplemental Index