Initiation of apoptosis in hepatocytes during prolonged arterial hypotension and postresuscitation period

Autor:	Nosova, N., Kozhura, V., Novoderzhkina, I.
Zdroj:	Bulletin of Experimental Biology and Medicine; March 1998, Vol. 125 Issue: 3 p251-254, 4p
Abstrakt:	Abstract: An increase in activity of Ca2+, Mg2+-dependent endonucleases on the second hour of hypotension coincided with the presence of DNA fragments in agarose gel. A correlation was established between the duration of hypotension, Ca2+, Mg2+-dependent endonuclease activity, and intensity of nuclear DNA fragmention. Apopotosis of hepatocytes is triggered during ischemia and develops during reperfusion.
Databáze:	Supplemental Index
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