| Autor: |
Gursel, G., Gokcora, N., Elbeg, S., Samurkasoglu, B., Ekim, N. |
| Zdroj: |
Tubercle and Lung Disease (now called Tuberculosis); August 1995, Vol. 76 Issue: 4 p370-371, 2p |
| Abstrakt: |
Our study was undertaken to investigate the role of tumor necrosis factor-alpha (TNF-@a) at the site of disease activity in tuberculous pleuritis (TP). Concentrations of TNF-@a were measured directly by radioimmunoassay (RIA) in the pleural fluid (PF) and plasma (P) of patients with TP (n = 14), malignant effusions (n = 18) and transudates (n = 7). Among these three groups mean plasma levels of TNF-@a were not statistically significant (P > 0.05), but in the TP group mean levels of TNF-@a in PF were significantly higher than in the cancer and transudate groups (P < 0.001), and there was no significant difference between the cancer and transudate groups (P > 0.05). These results may indicate a local synthesis of TNF-@a by cells within the pleural cavity in this disease. |
| Databáze: |
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| Externí odkaz: |
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