| Autor: |
Nühs, Andrea, Schäfer, Carola, Zander, Dorothea, Trübe, Leona, Tejera Nevado, Paloma, Schmidt, Sonja, Arevalo, Jorge, Adaui, Vanessa, Maes, Louis, Dujardin, Jean-Claude, Clos, Joachim |
| Zdroj: |
International Journal for Parasitology: Drugs & Drug Resistance; Apr2014, Vol. 4 Issue 1, p37-47, 11p |
| Abstrakt: |
Highlights: [•] Functional cloning identifies a Leishmania-specific 58kD antimony resistance marker, ARM58. [•] ARM58 overexpression confers antimony resistance. [•] A neighbouring, structurally related gene lacks antimony resistance function. [•] ARM58 comprises 4 related domains of unknown function, classified as DUF1935. [•] Cosmid-based functional cloning is feasible in L. braziliensis in spite of RNAi. [Copyright &y& Elsevier] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
