Discovery of 7-Tetrahydropyran-2-ylChromans:β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)Inhibitors That Reduce Amyloid β-Protein (Aβ) inthe Central Nervous System.
| Autor: | Thomas, Allen A., Hunt, Kevin W., Volgraf, Matthew, Watts, Ryan J., Liu, Xingrong, Vigers, Guy, Smith, Darin, Sammond, Douglas, Tang, Tony P., Rhodes, Susan P., Metcalf, Andrew T., Brown, Karin D., Otten, Jennifer N., Burkard, Michael, Cox, April A., Do, Mary K. Geck, Dutcher, Darrin, Rana, Sumeet, DeLisle, Robert K., Regal, Kelly |
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| Zdroj: | Journal of Medicinal Chemistry; Feb2014, Vol. 57 Issue 3, p878-902, 25p |
| Databáze: | Supplemental Index |
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